Alfin2400.blogspot.com Website Review

An as*orted mix of posts, some original, some favourites previously published in other Al Fin blogs. Years ago, ketamine was found to have an instant antidepressant effect -- even in depressed people who had failed to improve when taking conventional antidepressants. Ketamine caused improved moods within hours -- instead of several weeks with typical antidepressants. And the effect of just one dosage of ketamine lasted up to several weeks. The main problem with ketamine, for most people, is the Recent US clinical Phase IIA trials of the drug GLYX-13 -- a drug with similar neurological effects as ketamine -- show encouraging results for treating depression. Similar to ketamine in effect, but without the hallucinations. > The Phase IIa results show that a single administration of GLYX-13 > produced statistically significant reductions in depression scores > in subjects who had failed treatment with one or more antidepressant > agents. The reductions were evident within 24 hours and persisted > for an average of seven days. Importantly, the effect size, a > measure of the magnitude of the drug's antidepressant efficacy, > observed at 24 hours and at seven days after a single administration > of GLYX-13, was nearly double the effect size seen with most other > antidepressant drugs after 4-6 weeks of repeated dosing. >  > In the Phase IIa trial, GLYX-13 was well tolerated. Reported side > effects were mild to moderate and were consistent with those > observed in subjects receiving placebo. Consistent with previous > studies, GLYX-13 did not produce any of the schizophrenia-like Ever since Al Fin discovered the rapid antidepressant effects of ketamine, he has insisted that all Al Fin blog writers whose postings start to trend too dark, must come in to the office for an injection of ketamine from the blog physician's as*istant.