Cerenis.com Website Review

Specialized Committees—— Audit Committee—— Remuneration Committee—— Research Committee Our approach— About HDL and CVD— The commercial opportunity— The science of HDL HDL deficiency— What is HDL deficiency? Our therapies— CER 001— CER 209— Scientific presentation Media— Press releases— Events Investors— Regulated information— Shareholder meeting— Investor presentations— Corporate presentation — Cerenis on stock market— Investor Contacts— Financial Calendar Founded in 2005, Cerenis Thera*eutics is an international biopharmaceutical company dedicated to the discovery and development CERENIS’ expertise has translated into a rich portfolio of programs for the treatment of cardiovascular disease and as*ociated metabolic diseases such as NAFLD and NASH as well as a HDL targeted drug delivery platform in oncology, more specifically in immuno-oncology CERENIS is well positioned to become one of the leaders in the HDL thera*eutic market, with a broad portfolio of programs in development CER-001 is a bio-engineered complex of recombinant human apoA-I, the major structural protein of HDL, and phospholipids. It has been designed to mimic the structure and function of natural, nascent HDL, also known as pre-beta HDL. Its mechanism of action is to increase apoA-I and the number of HDL particles. SAMBA, the clinical Phase 2 study in patients with hypoalphalipoproteinemia due to genetic defects, has provided important data demonstrating the efficacy of CER-001 in regressing atherosclerosis in several distinct vascular beds, and leading to the TANGO study. The totality of the data to date indicates that CER-001 performs all of the functions of natural pre-beta HDL particles and has the potential to be the best-in-clas* HDL mimetic on the market HDL particles, loaded with an active agent, hold the promise to target and selectively kill malignant cells while sparing healthy ones. A wide variety of drugs can be embedded in these particles targeting markers specific to cancer cells and bring these potent drugs to their