Nestarenie.ru Website Review

Human aging is a dysfunction, breakdown of intracellular interactions, extracellular communications and systems of other interrelationships. A disease is a disorder, a disease is not a deviation from the norm. Human aging is a disease. Ways to eliminate such disorders, as well as methods to prevent them, are one of the most promising areas of modern aging. It is a leading risk factor for many cardiovascular diseases, in particular, due to significant changes in the geometry, composition, mechanical properties and functions of central arteries. These changes, as a rule, manifest themselves in the form of structural rigidity of these arteries, which, through changes in hemodynamics, increases the load on the heart and increases microvascular damage in organs such as the brain and kidneys. Among other causes, the old central arteries widen and become stiff in humans due to the mechanical fatigue of the medial elastic fibers and an increase in the number of cross-links of collagen fibers. These microstructural changes, in turn, increase the speed of the pulse wave in the femoral and carotid