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The history and clinical findings of MP Men 45 years old, which initially referred to memory loss and concentration power. With the loss of intelligence during the following years, he experienced involuntary movements of the fingers and toes, as well as facial and lumbar facial movements. He was depressed and self-conscious. She was already healthy and did not have a similar history of her relatives. His parents died in a car accident in the fifth decade of their life. M.P had a healthy gi*l. After extensive, specialist and internal evaluation of nerves, M.p. was diagnosed as Huntington's disease. The cause of Huntington's disease is a dominant autosomal dominant neurologic disorder that occurs in all races and is caused by mutations in the HD gene. The product of the HD gene, Huntington, appears everywhere. The function of this gene remains unknown. Pathogenic mutations in HD are usually due to the extension of a repeat sequence of CAG encoding polyglutamine in Exon 1. Natural HD alleles have about 10 to 26 repeats of CAG, while mutated alleles have more than 36 replicates. Approximately 3% of patients develop Huntington as a result of the repeated CAG extension, while 97% of the HD allele has a mutated parent of the parent They inherit. The occurrence of mutation Huntington caused neurologic impairment, atrophy